Is it possible to run the sequel to assassin's Creed? The requirements for Assassin's Creed 2 state that you will need at least 4 gigabytes of RAM. If you want to run Assassin's Creed 2, you have to have an Intel Core 2 Duo Q6739 processor. If you want to run AC2 with the highest settings, you should use anNVIDIA 8800 GT or better.