What is the meaning of the numbers lost?

Question

See numbers for the episode. The numbers 4, 8, 15, 16, 23 and 42 were frequently used in Lost. Jacob was going to be replaced by one of the final candidates. The coefficients of the equation predicted the extinction of mankind.

Hagrid P Hazard · Accepted Answer

See numbers for the episode. The numbers 4, 8, 15, 16, 23 and 42 were frequently used in Lost. Jacob was going to be replaced by one of the final candidates. The coefficients of the equation predicted the extinction of mankind.

What is the meaning of the numbers lost?

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